<?xml version="1.0" ?>
<histo xmlns="http://65.222.228.150/jjb/tma_cde.htm"
       xmlns:cpctr="http://www.pathology.pitt.edu/pdf/cpctr/cpctr-cde-v22.pdf"
       xmlns:dc="http://dublincore.org">
<tma>
<header>
<dc:title>Cooperative Prostate Cancer Tissue Resource (CPCTR) Prostate Cancer Microarray 2-D</dc:title>
<dc:creator>CPCTR</dc:creator>
<dc:subject>Prostate tissue microarray</dc:subject>
<dc:description>CPCTR TMA XML datafile for Microarray 2-D</dc:description>
<dc:publisher>CPCTR</dc:publisher>
<dc:contributor>CPCTR</dc:contributor>
<dc:date>2004-08-14</dc:date>
<dc:type>Prostate Cancer Tissue Microarray</dc:type>
<dc:format>XML in ASCII text</dc:format>
<dc:resource_identifier>http://www.prostatetissues.org</dc:resource_identifier>
<dc:source>CPCTR Tissue Microarray 2-D</dc:source>
<dc:language>En</dc:language>
<dc:relation>0001</dc:relation>
<dc:coverage>Jules J. Berman, Ph.D, M.D., National cancer Institute, EPN-6028 6130 Executive Boulevard Rockville, Maryland, USA, 21208 or Jonathan Melamed, M.D., New York University School of Medicine, 550 First Avenue TH468, New York, New York, USA, 10016</dc:coverage>
<dc:rights_management>CPCTR</dc:rights_management>
<filename>cpctr_2D.xml</filename>
</header>
<block>
<block_purpose>Prostate Cancer Tissue Microarray with outcomes data</block_purpose>
<block_description>prostate cancer tissue microarray with outcomes data created by Drs. Jonathan Melamed, Xiangtian Kong, and Yan Zhao for the CPCTR, prostatic cancer, prostatic adenocarcinoma, adenocarcinoma of prostate, carcinoma of prostate, tma, tissue micro array, tissue micro-array, tissue resource, tissue repository, nci, national cancer institute, marker, cancer test, validation, cpctr, cooperative prostate cancer tissue resource</block_description>
<block_meshnumbers>C04.588.945.440.770 C12.294.260.750 C12.294.565.625 C12.740.800.410.650 C04.557.470.200.240.500 G01.100.656 H01.158.100.656 E05.200.500.607.512 E05.200.750.551.512 E05.478.588 G01.201.344.512 G01.201.486.512 H01.158.201.344.512 H01.158.201.486.512</block_meshnumbers>
<block_relatedblocks>cpctr-02-C</block_relatedblocks>
<block_creator>Drs. Jonathan Melamed, Xiangtian Kong, and Yan Zhao</block_creator>
<block_creation_date>2004-7-7 with supplemental cores added 2004-8-5</block_creation_date>
<block_protocol>http://www.pathology.pitt.edu/pdf/cpctr/block.htm</block_protocol>
<block_number_of_cores>413</block_number_of_cores>
<block_qa>http://prostatetissues.org</block_qa>
<block_core_size>0.6 mm</block_core_size>
<block_array_hash>320 cores are arranged over a grid of 29 columns and 19 rows as 5 x 4 subarrays.  There are also 4 cell line cores located in row 5 from column 1-4.  26 additional cell lines and cores are located in a sidebar subarray in columns 25-26.  63 supplementary cores were added in an additional sidebar array in columns 26-28 and a partial additional row 20.  Each core location is given as a coordinate from 1,1 to 20,29.  When the slide is placed in front of you in the normal (microscope) view position with the cover-slip up and slide (frosted) label area to the left, the 1,1 core is the extreme left position closest to the person viewing the slide.  The 1,29 position is at the right end of the same row, closest to the end of the slide and furthest from the frosted end.  The 20, 29 position is the farthest right core in the row farthest from the viewer, farthest from the frosted end.  Sample subarrays for prostate cancer, benign prostate, HGPIN, and nodular hyperplasia tissues are distributed in a set of 16 subarrays, each with 5 x 4 cores, and located at (1, 1-5, 4), (1, 6-5, 9), (1, 11-5, 14), (1, 16-5, 19), (7, 1-11, 4), (7, 6-11, 9), (7, 11-11, 14), (7, 16-11, 19), (13, 1-17, 4), (13, 6-17, 9), (13, 11-17, 14), (13, 16-17, 19), (19, 1-23, 4), (19, 6-23, 9), (19, 11-23, 14), (19, 16-23, 19).  A separate sidebar of cell lines and prostate tissues is located in columns 25-26, including rows 1-19 in column 25 and rows 1-12 in column 26.  An additional sidebar of supplementary cores of prostate tissues is located in columns 26-28, including rows 13-19 in column 26, rows 4-19 in column 27, and rows 4-18 in column 28.  A partial additional row 20 also contains supplementary cores and includes columns 4-27.  Also, there are three liver cores located at 20,1 and 20,2, and 20,3.</block_array_hash>
<slide>
<slide_identifier>cpctr-02-D-001</slide_identifier>
<slide_cut_date>2004-8-6</slide_cut_date>
<slide_storage>room temperature in a lighted room in a vacuum dessicator</slide_storage>
<slide_section_thickness>4 microns</slide_section_thickness>
<slide_level>1</slide_level>
<slide_sectioning_protocol>http://www.pathology.pitt.edu/pdf/cpctr/section.htm</slide_sectioning_protocol>
<slide_stain>Hematoxylin and Eosin</slide_stain>
</slide>
<core>
<records>
	<record>
		<tissue_code>CL1</tissue_code>
		<Row>8</Row>
		<Column>1</Column>
		<Block>1</Block>
		<IMS_Case_Identifier></IMS_Case_Identifier>
		<Race></Race>
		<Month_of_Birth></Month_of_Birth>
		<Year_of_Birth></Year_of_Birth>
		<Month_of_Diagnosis></Month_of_Diagnosis>
		<Year_of_Diagnosis></Year_of_Diagnosis>
		<Month_of_Prostatectomy></Month_of_Prostatectomy>
		<Year_of_Prostatectomy></Year_of_Prostatectomy>
		<Is_Residual_Carcinoma_Present></Is_Residual_Carcinoma_Present>
		<Most_Prominent_Histologic_Type></Most_Prominent_Histologic_Type>
		<Gleason_Primary_Grade></Gleason_Primary_Grade>
		<Gleason_Secondary_Grade></Gleason_Secondary_Grade>
		<Gleason_Sum_Score></Gleason_Sum_Score>
		<Number_of_Nodes_Examined></Number_of_Nodes_Examined>
		<Number_of_Nodes_Positive></Number_of_Nodes_Positive>
		<Distant_Mets__1_at_Time_of_Diagn></Distant_Mets__1_at_Time_of_Diagn>
		<pT_Stage></pT_Stage>
		<pN_Stage></pN_Stage>
		<pM_Stage></pM_Stage>
		<Vital_Status></Vital_Status>
		<Month_of_PSA_Recurrence></Month_of_PSA_Recurrence>
		<Year_of_PSA_Recurrence></Year_of_PSA_Recurrence>
		<PSA_Recurrence_Status></PSA_Recurrence_Status>
		<Recurrence_Free_Month></Recurrence_Free_Month>
		<Recurrence_Free_Year></Recurrence_Free_Year>
		<Age_at_Diagnosis></Age_at_Diagnosis>
		<Age_at_Prostatectomy></Age_at_Prostatectomy>
		<Months_to_PSA_Recurrence></Months_to_PSA_Recurrence>
		<Months_PSA_Recurrence_Free></Months_PSA_Recurrence_Free>
	</record>
</records>
</core>
</block>
</tma>
</histo>

